John Dies at the End (2007)

Jason Pargin (writing as David Wong) crafts a slacker cosmic horror that leans gleefully into gonzo farce without diminishing its Lovecraftian dread. Dave and John are hopelessly underqualified exorcists navigating meat monsters, bizarre temporal shifts and the reality-shredding drug known as Soy Sauce. The gag rate is relentless, yet the grotesque body horror, gore and bleak philosophical panic are completely sincere. It works because the dread feels cosmically vast while the protagonists remain delightfully stubborn idiots.