Aqua Teen Hunger Force (2000)

Three fast food items, Master Shake, Frylock and Meatwad, share a house in South New Jersey and torment their neighbor Carl. Plots get set up mostly to be abandoned, and that is the joke: few shows commit this hard to going nowhere. It previewed on Cartoon Network in December 2000, became an Adult Swim staple in 2001 and wrapped in 2015, then came back for one more season in 2023, for 144 episodes in all, plus a 2007 theatrical movie. Episodes run about 11 minutes. Baffling level: high, but cheerfully so.