Y: The Last Man (2002)

FX on Hulu canceled its adaptation after a single season, so if you started it, this is the only way to find out how the story ends. Brian K. Vaughan and Pia Guerra's series ran for 60 issues from 2002 to 2008, following the last man left alive after every other mammal with a Y chromosome dies at once, and his trek across a world run by women. It is funnier and more of a globe-trotting adventure than the show's grim first season, and its ending is worth the whole trip.