Gloomhaven
The legacy here is a whole world rather than a single board. Finishing scenarios places illustrated location stickers on the city map, ability cards take enhancement stickers that change what they do, and 17 character classes wait, mostly sealed, for your group to unlock them. Each hero chases a personal goal and retires on reaching it, which pushes players into new classes and keeps a long campaign from going stale.
There are 95 main scenarios in a box that weighs about 21 pounds, so this suits a group ready to commit for many months of tactical card play, with the stickered map left behind as a record of everywhere your party has been.
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