Thomas Hunt Morgan

Thomas Hunt Morgan was openly sceptical in the 1900s of both Mendel's laws as a general explanation and the idea that genes sit on chromosomes. In 1910 a single white-eyed male fruit fly in his Columbia laboratory showed a pattern of inheritance tied to sex, and he changed course. With his students in the "fly room" he went on to map genes on chromosomes, winning the Nobel prize in 1933.